Ganesh S. Moorthy

Discovery of Dabrafenib: A Selective Inhibitor of Raf Kinases with Antitumor Activity against B-Raf-Driven Tumors

Tara Rheault, John Stellwagen, George M. Adjabeng et al. · ACS Medicinal Chemistry Letters · 2013 · 253 citations · Full text

B-raf-driven Tumors, Antitumor Activity, Hyperactive Signaling +16

Fasoracetam in adolescents with ADHD and glutamatergic gene network variants disrupting mGluR neurotransmitter signaling

Josephine Elia, Grace Ungal, Charlly Kao et al. · Nature Communications · 2017 · 91 citations · Full text

Optimization of 4,6-bis-anilino-1H-pyrrolo[2,3-d]pyrimidine IGF-1R tyrosine kinase inhibitors towards JNK selectivity

Stanley D. Chamberlain, Anikó M. Redman, Joseph W. Wilson et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 57 citations · Full text

Medicinal Chemistry, Biochemistry, Natural Sciences +8

Preclinical Drug Metabolism and Pharmacokinetic Evaluation of GW844520, A Novel Anti-Malarial Mitochondrial Electron Transport Inhibitor

Hong Xiang, Jeanelle McSurdy-Freed, Ganesh S. Moorthy et al. · Journal of Pharmaceutical Sciences · 2006 · 53 citations

Medicinal Chemistry, Pharmacokinetic Evaluation, Biochemistry +10

Population pharmacokinetics of midazolam and its metabolites in overweight and obese adolescents

Anne van Rongen, Janelle D. Vaughns, Ganesh S. Moorthy et al. · British Journal of Clinical Pharmacology · 2015 · 48 citations · Full text