Nathalie Wössner

Sirtuin 1 Inhibiting Thiocyanates (S1th)—A New Class of Isotype Selective Inhibitors of NAD+ Dependent Lysine Deacetylases

Nathalie Wössner, Zayan Alhalabi, Jessica González et al. · Frontiers in Oncology · 2020 · 36 citations · Full text

Medicine, Cancer Biology, Oncology +13

HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2)**

Matthias Schiedel, Attila Lehotzky, Sándor Szunyogh et al. · ChemBioChem · 2020 · 28 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +12

Development of a NanoBRET assay to validate inhibitors of Sirt2-mediated lysine deacetylation and defatty-acylation that block prostate cancer cell migration

Anja Vogelmann, Matthias Schiedel, Nathalie Wössner et al. · RSC Chemical Biology · 2022 · 28 citations · Full text

Medicine, Molecular Biology, Oncology +13

Structure–Reactivity Relationships on Substrates and Inhibitors of the Lysine Deacylase Sirtuin 2 from <i>Schistosoma mansoni</i> ( <i>Sm</i> Sirt2)

Daria Monaldi, Dante Rotili, Julien Lancelot et al. · Journal of Medicinal Chemistry · 2019 · 25 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Photochromic Indolyl Fulgimides as Chromo-pharmacophores Targeting Sirtuins

Nadja A. Simeth, Lisa‐Marie Altmann, Nathalie Wössner et al. · The Journal of Organic Chemistry · 2018 · 21 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13