Attila Lehotzky

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site

Tobias Rumpf, Matthias Schiedel, Berin Karaman et al. · Nature Communications · 2015 · 290 citations · Full text

Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals)

Matthias Schiedel, Daniel Herp, Sören Hammelmann et al. · Journal of Medicinal Chemistry · 2017 · 261 citations · Full text

Medicinal Chemistry, Biochemistry, Induced Degradation +15

Natively unfolded tubulin polymerization promoting protein TPPP/p25 is a common marker of alpha-synucleinopathies

Gábor G. Kovács, Lajos László, János Kovács et al. · Neurobiology of Disease · 2004 · 158 citations · Full text

Unfolded Tubulin Polymerization, Neurodegenerative Diseases, Protein Function +10

Tubulin polymerization‐promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation

Attila Lehotzky, Pierre Lau, Natália Tőkési et al. · Glia · 2009 · 133 citations

TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6

Natália Tőkési, Attila Lehotzky, István Horváth et al. · Journal of Biological Chemistry · 2010 · 106 citations · Full text

Molecular Regulation, Molecular Biology, Cytoskeleton +17