Walaa G. Hozayen

Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats

Ayman M. Mahmoud, Walaa G. Hozayen, Shimaa M. Ramadan · Biomedicine & Pharmacotherapy · 2017 · 166 citations

Veterinary Medicine, Biochemistry, Pharmacology +16

Ferulic acid protects against methotrexate nephrotoxicity<i>via</i>activation of Nrf2/ARE/HO-1 signaling and PPARγ, and suppression of NF-κB/NLRP3 inflammasome axis

Ayman M. Mahmoud, Omnia E. Hussein, Sanaa M. Abd El‐Twab et al. · Food & Function · 2019 · 152 citations

Medicine, Nephrology, Pharmacology +16

Methotrexate hepatotoxicity is associated with oxidative stress, and down-regulation of PPARγ and Nrf2: Protective effect of 18β-Glycyrrhetinic acid

Ayman M. Mahmoud, Omnia E. Hussein, Walaa G. Hozayen et al. · Chemico-Biological Interactions · 2017 · 151 citations

Veterinary Medicine, Pharmacology, Toxicology +17

Ferulic acid prevents oxidative stress, inflammation, and liver injury via upregulation of Nrf2/HO-1 signaling in methotrexate-induced rats

Ayman M. Mahmoud, Omnia E. Hussein, Walaa G. Hozayen et al. · Environmental Science and Pollution Research · 2019 · 145 citations

Life Sciences, Pharmacology, Toxicology +16

Cardiac and pulmonary toxicity of mesoporous silica nanoparticles is associated with excessive ROS production and redox imbalance in Wistar rats

Walaa G. Hozayen, Ayman M. Mahmoud, Ekram M. Desouky et al. · Biomedicine & Pharmacotherapy · 2018 · 115 citations · Full text

Pharmacy, Pharmacology, Toxicology +17