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Berberine ameliorates methotrexate-induced liver injury by activating Nrf2/HO-1 pathway and PPARγ, and suppressing oxidative stress and apoptosis in rats

InflammationRedox SignalingBiochemistryMethotrexate-induced Liver InjuryMedicineLiver PhysiologyCell DeathHepatotoxicityReactive Oxygen SpecieNrf2/ho-1 PathwayMetabolic SignalingPharmacologyRedox BiologyDrug-induced Liver InjuryOxidative Stress