NINJ1 mediates plasma membrane rupture during lytic cell death

Nobuhiko Kayagaki, Opher S. Kornfeld, Bettina L. Lee, +24

Nature

Reactive Nitrogen SpecieNitrosative StressCell DeathPlasma Membrane RuptureCellular Biochemistry +4

Activity of caspase-8 determines plasticity between cell death pathways

Kim Newton, Katherine E. Wickliffe, Allie Maltzman, +8

Nature

Signal TransductionSignaling PathwayCell RegulationApoptosisCell Death Pathways +6

The first Korean genome sequence and analysis: Full genome sequencing for a socio-ethnic group

Sung‐Min Ahn, Tae‐Hyung Kim, Sunghoon Lee, +18

Genome Research

GeneticsHuman PolymorphismReference GenomesGenomicsMolecular Ecology +16

IRF2 transcriptionally induces <i>GSDMD</i> expression for pyroptosis

Nobuhiko Kayagaki, Bettina L. Lee, Irma B. Stowe, +16

Science Signaling

Shigella ubiquitin ligase IpaH7.8 targets gasdermin D for degradation to prevent pyroptosis and enable infection

Giovanni Luchetti, Justin L. Roncaioli, Roberto A. Chavez, +16

Cell Host & Microbe

Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling

Jeffrey K. Holden, James J. Crawford, Cameron L. Noland, +17

Cell Reports

Lipid PeroxidationLipid TailTumor BiologyOxidative StressInflammation +15

Ubiquitin Ligase COP1 Suppresses Neuroinflammation by Degrading c/EBPβ in Microglia

Ada Ndoja, Rohit Reja, Seung-Hye Lee, +11

Cell

InflammationNeurodegenerative DiseasesMolecular NeuroscienceMedicineCell Death +8

Molecular mechanisms of ribosomal protein gene coregulation

Rohit Reja, Vinesh Vinayachandran, Sujana Ghosh, +1

Genes & Development

The Nuclear Pore-Associated TREX-2 Complex Employs Mediator to Regulate Gene Expression

Maren Schneider, Doris Hellerschmied, Tobias Schubert, +6

Cell

Nuclear Pore ComplexesTranscriptional RegulationSignal TransductionMolecular RegulationNatural Sciences +12

Intrinsic apoptosis shapes the tumor spectrum linked to inactivation of the deubiquitinase BAP1

Meng He, Mira S. Chaurushiya, Joshua D. Webster, +14

Science