Grit Lorenczewski

Extremely potent, rapid and costimulation‐independent cytotoxic T‐cell response against lymphoma cells catalyzed by a single‐chain bispecific antibody

Torsten Dreier, Grit Lorenczewski, Christian Brandl et al. · International Journal of Cancer · 2002 · 349 citations · Full text

Immunology, Immunologic Mechanism, Cd4 T Cell Responses +19

T Cell Costimulus-Independent and Very Efficacious Inhibition of Tumor Growth in Mice Bearing Subcutaneous or Leukemic Human B Cell Lymphoma Xenografts by a CD19-/CD3- Bispecific Single-Chain Antibody Construct

Torsten Dreier, Patrick A. Baeuerle, Iduna Fichtner et al. · The Journal of Immunology · 2003 · 194 citations · Full text

Lymphoid Neoplasia, Cancer Immunosurveillance, Therapeutic Effect +14

T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells

Ralf Lutterbuese, Tobias Raum, Roman Kischel et al. · Proceedings of the National Academy of Sciences · 2010 · 160 citations · Full text

Braf-mutated Crc Lines, Cancer Immunosurveillance, Low Doses Growth +11

Eradication of Tumors from a Human Colon Cancer Cell Line and from Ovarian Cancer Metastases in Immunodeficient Mice by a Single-Chain Ep-CAM-/CD3-Bispecific Antibody Construct

Bernd Schlereth, Iduna Fichtner, Grit Lorenczewski et al. · Cancer Research · 2005 · 127 citations

Bispecific T-cell Engager, Immunology, Ovarian Cancer Metastases +18

T-cell activation and B-cell depletion in chimpanzees treated with a bispecific anti-CD19/anti-CD3 single-chain antibody construct

Bernd Schlereth, Cornelia Quadt, Torsten Dreier et al. · Cancer Immunology Immunotherapy · 2005 · 103 citations · Full text

Autoimmune Disease, Lymphocyte Development, Adaptive Immune System +10