Concepedia
Statistics
Publications
25
Citations
2.3K
H-Index
20
Active since
2001
Affiliations
Amgen (Germany)(Current)
Amgen (United States)
Ludwig-Maximilians-Universität München
German Cancer Research Center
3D-Micromac (Germany)
Roman Kischel is an author at Amgen (Germany) specializing in immunology, cancer immunology, and cancer immunotherapy.
Publications per year
2001–2025
Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism
Christina Krupka, Peter Kufer, Roman Kischel et al. · Leukemia · 2015 · 249 citations
Life Sciences, Immunology, Oncology +16
T-cell exhaustion induced by continuous bispecific molecule exposure is ameliorated by treatment-free intervals
Nora Philipp, Maryam Kazerani, Alyssa Nicholls et al. · Blood · 2022 · 245 citations · Full text
Life Sciences, Immunology, Oncology +17
CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell–engaging antibody AMG 330
Christina Krupka, Peter Kufer, Roman Kischel et al. · Blood · 2013 · 207 citations
Life Sciences, Immunology, Molecular Biology +17
Cellular determinants for preclinical activity of a novel CD33/CD3 bispecific T-cell engager (BiTE) antibody, AMG 330, against human AML
George S. Laszlo, Chelsea J. Gudgeon, Kimberly H. Harrington et al. · Blood · 2013 · 173 citations · Full text
Life Sciences, Immunology, Oncology +14
T cell-engaging BiTE antibodies specific for EGFR potently eliminate KRAS- and BRAF-mutated colorectal cancer cells
Ralf Lutterbuese, Tobias Raum, Roman Kischel et al. · Proceedings of the National Academy of Sciences · 2010 · 167 citations
Medicine, Oncology, Pharmacology +17
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