Cornelia Quadt

Convergent loss of PTEN leads to clinical resistance to a PI(3)Kα inhibitor

Dejan Juric, Pau Castel, Malachi Griffith et al. · Nature · 2014 · 561 citations · Full text

Signal Transduction, Clinical Resistance, Signaling Pathway +8

Phosphatidylinositol 3-Kinase α–Selective Inhibition With Alpelisib (BYL719) in <i>PIK3CA</i>-Altered Solid Tumors: Results From the First-in-Human Study

Dejan Juric, Jordi Rodón, Josep Tabernero et al. · Journal of Clinical Oncology · 2018 · 425 citations

Breast Oncology, Single-agent Alpelisib, Solid Tumors +17

mTORC1 Inhibition Is Required for Sensitivity to PI3K p110α Inhibitors in <i>PIK3CA</i> -Mutant Breast Cancer

Moshe Elkabets, Sadhna Vora, Dejan Juric et al. · Science Translational Medicine · 2013 · 344 citations · Full text

Alpelisib Plus Fulvestrant in <i>PIK3CA</i> -Altered and <i>PIK3CA</i> -Wild-Type Estrogen Receptor–Positive Advanced Breast Cancer

Dejan Juric, Filip Jankú, Jordi Rodón et al. · JAMA Oncology · 2018 · 256 citations · Full text

NVP-AUY922: a small molecule HSP90 inhibitor with potent antitumor activity in preclinical breast cancer models

Michael Rugaard Jensen, Joseph Schoepfer, Thomas Radimerski et al. · Breast Cancer Research · 2008 · 222 citations · Full text