Shannon M. Matulis

Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia

Adriana E. Tron, Matthew A. Belmonte, Ammar Adam et al. · Nature Communications · 2018 · 479 citations · Full text

Dexamethasone treatment promotes Bcl-2 dependence in multiple myeloma resulting in sensitivity to venetoclax

Shannon M. Matulis, Vikas A. Gupta, A K Nooka et al. · Leukemia · 2015 · 132 citations · Full text

Hematological Malignancy, Lymphoid Neoplasia, Autoimmune Disease +8

Distribution of Bim determines Mcl-1 dependence or codependence with Bcl-xL/Bcl-2 in Mcl-1–expressing myeloma cells

Alejo A. Morales, Metin Kurtoğlu, Shannon M. Matulis et al. · Blood · 2011 · 128 citations · Full text

Bone marrow microenvironment–derived signals induce Mcl-1 dependence in multiple myeloma

Vikas A. Gupta, Shannon M. Matulis, Jason E. Conage‐Pough et al. · Blood · 2017 · 109 citations · Full text

Targeting glutamine metabolism in multiple myeloma enhances BIM binding to BCL-2 eliciting synthetic lethality to venetoclax

Richa Bajpai, Shannon M. Matulis, Changyong Wei et al. · Oncogene · 2015 · 98 citations · Full text

Hematological Malignancy, Glutamine Metabolism, Medicine +10