Michele Sue‐Ann Woo

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cai‐Hong Yun, Kristen E. Mengwasser, Angela V. Toms et al. · Proceedings of the National Academy of Sciences · 2008 · 2.1K citations · Full text

Atp Binding Pocket, Molecular Biology, T790m Mutation +20

Structures of Lung Cancer-Derived EGFR Mutants and Inhibitor Complexes: Mechanism of Activation and Insights into Differential Inhibitor Sensitivity

Cai‐Hong Yun, Titus J. Boggon, Yiqun Li et al. · Cancer Cell · 2007 · 1.1K citations · Full text

Medicine, Inhibitor Complexes, Bronchial Neoplasm +6

Characterizing the cancer genome in lung adenocarcinoma

Barbara A. Weir, Michele Sue‐Ann Woo, Gad Getz et al. · Nature · 2007 · 1.1K citations · Full text

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

Adam J. Bass, Hideo Watanabe, Craig H. Mermel et al. · Nature Genetics · 2009 · 944 citations · Full text

Tumor Biology, Oncogenic Agent, Medicine +9

A murine lung cancer co-clinical trial identifies genetic modifiers of therapeutic response

Chen Zhao, Katherine A. Cheng, Zandra E. Walton et al. · Nature · 2012 · 447 citations

Oncology, Oncogenic Agent, Medicine +9