Kristen E. Mengwasser

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cai‐Hong Yun, Kristen E. Mengwasser, Angela V. Toms et al. · Proceedings of the National Academy of Sciences · 2008 · 2.1K citations · Full text

Medicine, Oncology, Pharmacology +14

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

Teresa Davoli, Andrew Wei Xu, Kristen E. Mengwasser et al. · Cell · 2013 · 892 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen E. Mengwasser, Richard O. Adeyemi, Yumei Leng et al. · Molecular Cell · 2019 · 203 citations · Full text

Life Sciences, Genetics, Molecular Biology +12

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser et al. · Cell Reports · 2019 · 49 citations · Full text

Medicine, Genetics, Oncology +17

Hirudin Binding Reveals Key Determinants of Thrombin Allostery

Kristen E. Mengwasser, Leslie A. Bush, Peter Shih et al. · Journal of Biological Chemistry · 2005 · 36 citations · Full text

Medicine, Biochemistry, Molecular Biology +14