Kristen E. Mengwasser

The T790M mutation in EGFR kinase causes drug resistance by increasing the affinity for ATP

Cai‐Hong Yun, Kristen E. Mengwasser, Angela V. Toms et al. · Proceedings of the National Academy of Sciences · 2008 · 2.1K citations · Full text

Atp Binding Pocket, Molecular Biology, T790m Mutation +20

Cumulative Haploinsufficiency and Triplosensitivity Drive Aneuploidy Patterns and Shape the Cancer Genome

Teresa Davoli, Andrew Wei Xu, Kristen E. Mengwasser et al. · Cell · 2013 · 873 citations · Full text

Chromatin, Genome Instability, Cumulative Haploinsufficiency +8

Genetic Screens Reveal FEN1 and APEX2 as BRCA2 Synthetic Lethal Targets

Kristen E. Mengwasser, Richard O. Adeyemi, Yumei Leng et al. · Molecular Cell · 2019 · 194 citations · Full text

Genetics, Synthetic Biology, Genetic Mechanism +4

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

Jessica S. Elman, Thomas K. Ni, Kristen E. Mengwasser et al. · Cell Reports · 2019 · 46 citations · Full text

Hirudin Binding Reveals Key Determinants of Thrombin Allostery

Kristen E. Mengwasser, Leslie A. Bush, Peter Shih et al. · Journal of Biological Chemistry · 2005 · 36 citations · Full text