Karine G. Harutyunyan

Selective BCL-2 Inhibition by ABT-199 Causes On-Target Cell Death in Acute Myeloid Leukemia

Rongqing Pan, Leah J. Hogdal, Juliana M. Benito et al. · Cancer Discovery · 2013 · 717 citations · Full text

Spectrum of CHD7 Mutations in 110 Individuals with CHARGE Syndrome and Genotype-Phenotype Correlation

Seema R. Lalani, Arsalan M. Safiullah, Susan Fernbach et al. · The American Journal of Human Genetics · 2006 · 391 citations · Full text

Mendelian Disorder, Chd7 Mutations, Genetic Disorder +8

MLL-Rearranged Acute Lymphoblastic Leukemias Activate BCL-2 through H3K79 Methylation and Are Sensitive to the BCL-2-Specific Antagonist ABT-199

Juliana M. Benito, Laura Godfrey, Kensuke Kojima et al. · Cell Reports · 2015 · 152 citations · Full text

Hematological Malignancy, Specific Molecular Pathways, H3k79 Methylation +15

Glutaminase Activity of <scp>L</scp> -Asparaginase Contributes to Durable Preclinical Activity against Acute Lymphoblastic Leukemia

Wai-Kin Chan, Thomas D. Horvath, Lin Tan et al. · Molecular Cancer Therapeutics · 2019 · 75 citations

Hypoxia-Activated Prodrug TH-302 Targets Hypoxic Bone Marrow Niches in Preclinical Leukemia Models

Juliana Benito, Marc S. Ramirez, Niki M. Zacharias et al. · Clinical Cancer Research · 2015 · 72 citations · Full text