Christoph W. Zapf - Concepedia

Author

Christoph W. Zapf

Pfizer (United States)ORCID

Also Known As

C. ZAPF, Christoph W Zapf, Christoph W. Zapf, Christoph Zapf, Zapf W. Christoph, Zapf, Christoph W.

Publications

1.1K

Citations

H-Index

Concepts

All Affiliations

Pfizer (United States)University of California San Diego Pearl River Community College Princeton University

About

Christoph W. Zapf is an author at Pfizer (United States) specializing in pharmacology, medicine, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	9	9	224
2	Natural Sciences	5	5	319
3	Biochemistry	4	4	296
4	Engineering	2	2	248
5	Biomolecular Engineering	2	2	248

Christoph W. Zapf

Publications

Citations

H-Index

Page 1

	Year	Citations
Diprotected Triflylguanidines: A New Class of Guanidinylation Reagents Konrad Feichtinger, Christoph W. Zapf, Heather L. Sings, The Journal of Organic Chemistry Derivative (Chemistry)Molecular SciencesBioorganic ChemistryEngineeringBiochemistry	1998	212
Chemoselective Electrosynthesis Using Rapid Alternating Polarity Yu Kawamata, Kyohei Hayashi, Ethan Carlson, Journal of the American Chemical Society	2021	169
Discovery of Clinical Candidate 1-{[(2 <i>S</i> ,3 <i>S</i> ,4 <i>S</i> )-3-Ethyl-4-fluoro-5-oxopyrrolidin-2-yl]methoxy}-7-methoxyisoquinoline-6-carboxamide (PF-06650833), a Potent, Selective Inhibitor of Interleukin-1 Receptor Associated Kinase 4 (IRAK4), by Fragment-Based Drug Design Katherine L. Lee, Catherine M. Ambler, David R. Anderson, Journal of Medicinal Chemistry	2017	138
A Diels–Alder Macrocyclization Enables an Efficient Asymmetric Synthesis of the Antibacterial Natural Product Abyssomicin C Christoph W. Zapf, Bryce A. Harrison, CARMEN DRAHL, Angewandte Chemie International Edition	2005	110
Covalent Inhibitors of Interleukin-2 Inducible T Cell Kinase (Itk) with Nanomolar Potency in a Whole-Blood Assay Christoph W. Zapf, Brian S. Gerstenberger, Xing Li, Journal of Medicinal Chemistry	2012	77
A Diels–Alder Macrocyclization Enables an Efficient Asymmetric Synthesis of the Antibacterial Natural Product Abyssomicin C Christoph W. Zapf, Bryce A. Harrison, CARMEN DRAHL, Angewandte Chemie Bioorganic ChemistryEngineeringBiochemistrySynthese DesNatural Sciences	2005	36
Discovery of a stable macrocyclic o-aminobenzamide Hsp90 inhibitor which significantly decreases tumor volume in a mouse xenograft model Christoph W. Zapf, Jonathan D. Bloom, Zhong Li, Bioorganic & Medicinal Chemistry Letters Mouse Xenograft ModelTumor BiologyMedicineAnti-cancer AgentCancer Treatment	2011	34
Solid-Phase Synthesis of Pyridones and Pyridopyrazines as Peptidomimetic Scaffolds Christopher J. Creighton, Christoph W. Zapf, Jane H. Bu, Organic Letters Combinatorial ChemistryMedicinal ChemistrySolid PhaseSolid-phase SynthesisHeterocyclic	1999	33
Discovery of 3-Cyano- <i>N</i> -(3-(1-isobutyrylpiperidin-4-yl)-1-methyl-4-(trifluoromethyl)-1 <i>H</i> -pyrrolo[2,3- <i>b</i> ]pyridin-5-yl)benzamide: A Potent, Selective, and Orally Bioavailable Retinoic Acid Receptor-Related Orphan Receptor C2 Inverse Agonist Mark E. Schnute, Mattias Wennerstål, Jennifer Alley, Journal of Medicinal Chemistry	2018	32
A Novel Traceless Resin-Bound Guanidinylating Reagent for Secondary Amines To Prepare <i>N</i>,<i>N</i>-Disubstituted Guanidines Christoph W. Zapf, Christopher J. Creighton, Mika Tomioka, Organic Letters	2001	30

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