Francesco Samarelli

Synthesis, computational and experimental pharmacological studies for (thio)ether-triazine 5-HT6R ligands with noticeable action on AChE/BChE and chalcogen-dependent intrinsic activity in search for new class of drugs against Alzheimer's disease

Kinga Czarnota-Łydka, Sylwia Sudoł-Tałaj, Katarzyna Kucwaj‐Brysz et al. · European Journal of Medicinal Chemistry · 2023 · 18 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Novel 6-alkyl-bridged 4-arylalkylpiperazin-1-yl derivatives of azepino[4,3-b]indol-1(2H)-one as potent BChE-selective inhibitors showing protective effects against neurodegenerative insults

Francesco Samarelli, Rosa Purgatorio, Gianfranco Lopopolo et al. · European Journal of Medicinal Chemistry · 2024 · 15 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +16

Assessing the Role of a Malonamide Linker in the Design of Potent Dual Inhibitors of Factor Xa and Cholinesterases

Rosa Purgatorio, Nicola Gambacorta, Francesco Samarelli et al. · Molecules · 2022 · 11 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Pleiotropic Effects of Direct Oral Anticoagulants in Chronic Heart Failure and Atrial Fibrillation: Machine Learning Analysis

Marco Mele, Antonietta Mele, Paola Imbrici et al. · Molecules · 2024 · 10 citations · Full text

Medicine, Cardiology, Pharmacology +17