Jacques Houtmann

Structural Basis for Human Monoglyceride Lipase Inhibition

Thomas Bertrand, Franck Augé, Jacques Houtmann et al. · Journal of Molecular Biology · 2009 · 164 citations

Lipid Science, Lipids, Biochemistry +1

Selective blockade of the hydrolysis of the endocannabinoid 2-arachidonoylglycerol impairs learning and memory performance while producing antinociceptive activity in rodents

Guy Griebel, Philippe Pichat, Sandra Beeské et al. · Scientific Reports · 2015 · 109 citations · Full text

Discovery and Pharmacokinetic and Pharmacological Properties of the Potent and Selective MET Kinase Inhibitor 1-{6-[6-(4-Fluorophenyl)-[1,2,4]triazolo[4,3-<i>b</i>]pyridazin-3-ylsulfanyl]benzothiazol-2-yl}-3-(2-morpholin-4-ylethyl)urea (SAR125844)

Antonio Ugolini, Mireille Kenigsberg, Alexey Rak et al. · Journal of Medicinal Chemistry · 2016 · 29 citations · Full text

Drug Target, Pharmacotherapy, Pharmaceutical Chemistry +18

KRAS G12C fragment screening renders new binding pockets

Magali Mathieu, Valérie Steier, Florence Fassy et al. · Small GTPases · 2021 · 22 citations · Full text

X-ray Crystallography, Drug Target, Engineering +18