Laurie K. Overton

Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-α

Marcia L. Moss, S.-L. Catherine Jin, Marcos E. Milla et al. · Nature · 1997 · 1.6K citations

Protein Expression, Medicine, Disintegrin Metalloproteinase +8

Agouti protein is an antagonist of the melanocyte-stimulating-hormone receptor

Dongsi Lu, Derril H. Willard, Indravadan R. Patel et al. · Nature · 1994 · 1.1K citations

Signal Transduction, G Protein-coupled Receptor, Medicine +8

High level expression of mammalian protein farnesyltransferase in a baculovirus system. The purified protein contains zinc

Wei J. Chen, John F. Moomaw, Laurie K. Overton et al. · Journal of Biological Chemistry · 1993 · 95 citations · Full text

Viral Replication, Molecular Biology, Individual Subunits +17

A Scintillation Proximity Assay for the Raf/MEK/ERK Kinase Cascade: High-Throughput Screening and Identification of Selective Enzyme Inhibitors

Octerloney B. McDonald, Wen Ji Chen, Byron Ellis et al. · Analytical Biochemistry · 1999 · 69 citations

Drug Target, Hit Identification, Biochemistry +11

17.beta.-(N-tert-Butylcarbamoyl)-4-aza-5.alpha.-androstan-1-en-3-one Is an Active Site-Directed Slow Time-Dependent Inhibitor of Human Steroid 5.alpha.-Reductase 1

Gaochao Tian, J. Darren Stuart, Marcia L. Moss et al. · Biochemistry · 1994 · 51 citations