Concepedia

Christophe J. De Saedeleer

CJ

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Publications

8

Citations

3.6K

H-Index

8

Active since

2008

Affiliations

UCLouvain(Current)

University of Namur

Duke University Hospital

Duke Medical Center

Christophe J. De Saedeleer is an author at UCLouvain specializing in cell biology, medicine, and cancer research.

Top concepts

MedicineCell BiologyBiochemistryTumor BiologyCancer BiologyCancer ResearchCancer MetabolismRadiation OncologyMetabolismBreast Cancer

Publications per year

2008–2015

8

Publications

8

Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice

Pierre Sonveaux, Frédérique Végran, Thies Schroeder et al. · Journal of Clinical Investigation · 2008 · 1.6K citations · Full text

Chemoprevention Strategy, Metabolic Remodeling, Cancer Biology +18

A Mitochondrial Switch Promotes Tumor Metastasis

Paolo E. Porporato, Valéry L. Payen, Jhudit Pérez‐Escuredo et al. · Cell Reports · 2014 · 590 citations · Full text

Targeting the Lactate Transporter MCT1 in Endothelial Cells Inhibits Lactate-Induced HIF-1 Activation and Tumor Angiogenesis

Pierre Sonveaux, Tamara Copetti, Christophe J. De Saedeleer et al. · PLoS ONE · 2012 · 511 citations · Full text

Endothelial Cells, Lactate Influx, Metabolic Remodeling +19

Lactate Activates HIF-1 in Oxidative but Not in Warburg-Phenotype Human Tumor Cells

Christophe J. De Saedeleer, Tamara Copetti, Paolo E. Porporato et al. · PLoS ONE · 2012 · 250 citations · Full text

Cancer Metabolism, Biochemistry, Oncogenic Agent +14

Lactate stimulates angiogenesis and accelerates the healing of superficial and ischemic wounds in mice

Paolo E. Porporato, Valéry L. Payen, Christophe J. De Saedeleer et al. · Angiogenesis · 2012 · 243 citations

Inflammation, Angiogenesis, Physiology +9

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