Simeon Rüdesheim

Physiologically Based Pharmacokinetic Modeling of Metoprolol Enantiomers and α-Hydroxymetoprolol to Describe CYP2D6 Drug-Gene Interactions

Simeon Rüdesheim, Jan‐Georg Wojtyniak, Dominik Selzer et al. · Pharmaceutics · 2020 · 25 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Physiologically‐based pharmacokinetic modeling of dextromethorphan to investigate interindividual variability within CYP2D6 activity score groups

Simeon Rüdesheim, Dominik Selzer, Uwe Fuhr et al. · CPT Pharmacometrics & Systems Pharmacology · 2022 · 24 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Physiologically based pharmacokinetic modeling of tacrolimus for <scp>food–drug</scp> and <scp>CYP3A drug–drug–gene</scp> interaction predictions

Helena Leonie Hanae Loer, Denise Feick, Simeon Rüdesheim et al. · CPT Pharmacometrics & Systems Pharmacology · 2023 · 20 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Novel models for the prediction of drug–gene interactions

Denise Türk, Laura Maria Fuhr, Fatima Zahra Marok et al. · Expert Opinion on Drug Metabolism & Toxicology · 2021 · 14 citations

Pharmacy, Pharmacokinetics, Pharmacology +17

Physiologically Based Pharmacokinetic Modeling to Describe the CYP2D6 Activity Score-Dependent Metabolism of Paroxetine, Atomoxetine and Risperidone

Simeon Rüdesheim, Dominik Selzer, Thomas E. Mürdter et al. · Pharmaceutics · 2022 · 12 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17