Helena Leonie Hanae Loer

Physiologically based pharmacokinetic modeling of tacrolimus for <scp>food–drug</scp> and <scp>CYP3A drug–drug–gene</scp> interaction predictions

Helena Leonie Hanae Loer, Denise Feick, Simeon Rüdesheim et al. · CPT Pharmacometrics & Systems Pharmacology · 2023 · 20 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +15

Physiologically Based Pharmacokinetic (PBPK) Modeling of Clopidogrel and Its Four Relevant Metabolites for CYP2B6, CYP2C8, CYP2C19, and CYP3A4 Drug–Drug–Gene Interaction Predictions

Helena Leonie Hanae Loer, Denise Türk, José David Gómez‐Mantilla et al. · Pharmaceutics · 2022 · 13 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17

Physiologically‐based pharmacokinetic modeling of quinidine to establish a <scp>CYP3A4</scp>, P‐gp, and <scp>CYP2D6 drug–drug–gene</scp> interaction network

Denise Feick, Simeon Rüdesheim, Fatima Zahra Marok et al. · CPT Pharmacometrics & Systems Pharmacology · 2023 · 11 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Physiologically based pharmacokinetic modeling of imatinib and <i>N</i>‐desmethyl imatinib for drug–drug interaction predictions

Helena Leonie Hanae Loer, Christina Kovar, Simeon Rüdesheim et al. · CPT Pharmacometrics & Systems Pharmacology · 2024 · 11 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17