Hema Negi

Tumor-secreted anterior gradient-2 binds to VEGF and FGF2 and enhances their activities by promoting their homodimerization

Hao Guo, Qi Zhu, Xiaoyan Yu et al. · Oncogene · 2017 · 111 citations

Developmental Biology, Fibroblast Growth Factor, Cell Proliferation +9

Anterior Gradient-2 monoclonal antibody inhibits lung cancer growth and metastasis by upregulating p53 pathway and without exerting any toxicological effects: A preclinical study

Hema Negi, Siva Bharath Merugu, Hitesh Bhagavanbhai Mangukiya et al. · Cancer Letters · 2019 · 63 citations

Oncology, Medicine, Preclinical Study +13

Anterior gradient 2 is induced in cutaneous wound and promotes wound healing through its adhesion domain

Qi Zhu, Hitesh Bhagavanbhai Mangukiya, Dhahiri Saidi Mashausi et al. · FEBS Journal · 2017 · 60 citations · Full text

Tissue Engineering, Anterior Gradient 2, Dermatology +16

Binding of anterior gradient 2 and estrogen receptor-α: Dual critical roles in enhancing fulvestrant resistance and IGF-1-induced tumorigenesis of breast cancer

Zheqi Li, Qi Zhu, Hao Chen et al. · Cancer Letters · 2016 · 29 citations

Fulvestrant Resistance, Anterior Gradient 2, Breast Oncology +12

Induction of anterior gradient 2 (AGR2) plays a key role in insulin-like growth factor-1 (IGF-1)-induced breast cancer cell proliferation and migration

Zheqi Li, Zhenghua Wu, Hao Chen et al. · Medical Oncology · 2015 · 28 citations · Full text