An Epithelial–Mesenchymal Transition Gene Signature Predicts Resistance to EGFR and PI3K Inhibitors and Identifies Axl as a Therapeutic Target for Overcoming EGFR Inhibitor Resistance

Lauren A. Byers, Lixia Diao, Jing Wang, +31

Clinical Cancer Research

Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenecity of human platelets

Hansjörg Schwertz, Neal D. Tolley, Jason M. Foulks, +10

The Journal of Experimental Medicine

mTOR-dependent synthesis of Bcl-3 controls the retraction of fibrin clots by activated human platelets

Andrew S. Weyrich, Melvin M. Denis, Hansjörg Schwertz, +7

Blood

The Renal Excretion of Potassium.

Gilbert H. Mudge, Jason M. Foulks, Alfred G. Gilman

Experimental Biology and Medicine

UrologyRenal FunctionBiochemistrySodium HomeostasisMedicine +13

A Small-Molecule Inhibitor of PIM Kinases as a Potential Treatment for Urothelial Carcinomas

Jason M. Foulks, Kent J. Carpenter, Bai Luo, +22

Neoplasia

Pharmacologic Activation of PKM2 Slows Lung Tumor Xenograft Growth

K. Mark Parnell, Jason M. Foulks, Rebecca N. Nix, +16

Molecular Cancer Therapeutics

Synthesis and Biological Evaluation of Pyrazolo[1,5-<i>a</i>]pyrimidine Compounds as Potent and Selective Pim-1 Inhibitors

Yong Xu, Benjamin Brenning, Steven G. Kultgen, +8

ACS Medicinal Chemistry Letters

Pim-1 InhibitorsSelective Pim-1 InhibitorsCellular PharmacologyPharmacotherapyLead Compound +19

Intracellular PAF catabolism by PAF acetylhydrolase counteracts continual PAF synthesis

Jiawei Chen, Lili Yang, Jason M. Foulks, +3

Journal of Lipid Research

Discovery of 3-(trifluoromethyl)-1H-pyrazole-5-carboxamide activators of the M2 isoform of pyruvate kinase (PKM2)

Yong Xu, Xiaohui Liu, Michael A. Saunders, +11

Bioorganic & Medicinal Chemistry Letters

Pharmaceutical ChemistryBiochemistryMedicineNatural SciencesMechanism Of Action +6

A yeast PAF acetylhydrolase ortholog suppresses oxidative death

Jason M. Foulks, Andrew S. Weyrich, Guy A. Zimmerman, +1

Free Radical Biology and Medicine

BiochemistryCell DeathYeastOxidative DeathMedicine +1