Kaushik Mitra - Concepedia

Author

Kaushik Mitra

Merck & Co., Inc., Rahway, NJ, USA (United States)ORCID

Also Known As

K Mitra, K. MITRA, K. Mitra, Kaushik Mitra

Publications

871

Citations

H-Index

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)University of Missouri Massachusetts Institute of Technology Janssen (United States)

About

Kaushik Mitra is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in pharmacology, medicine, and biochemistry.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	10	10	355
2	Natural Sciences	9	9	312
3	Biochemistry	9	9	311
4	Engineering	3	3	47
5	Biomolecular Engineering	3	3	57

Kaushik Mitra

Publications

720

Citations

H-Index

Page 1

	Year	Citations
Oxidative DNA Cleavage by the Antitumor Antibiotic Leinamycin and Simple 1,2-Dithiolan-3-one 1-Oxides: Evidence for Thiol-Dependent Conversion of Molecular Oxygen to DNA-Cleaving Oxygen Radicals Mediated by Polysulfides Kaushik Mitra, Woongki Kim, J. Scott Daniels, Journal of the American Chemical Society Bioorganic ChemistryAltmetric Attention ScoreMolecular BiologyChemical BiologyThiol-dependent Conversion	1997	94
Discovery of Novel Indoline Cholesterol Ester Transfer Protein Inhibitors (CETP) through a Structure-Guided Approach Jonathan E. Wilson, Ravi Kurukulasuriya, Mikhail Reibarkh, ACS Medicinal Chemistry Letters	2016	52
A Rationally Designed Genotoxin that Selectively Destroys Estrogen Receptor-Positive Breast Cancer Cells Kaushik Mitra, John C. Marquis, Shawn Hillier, Journal of the American Chemical Society	2002	49
Minimizing metabolic activation during pharmaceutical lead optimization: progress, knowledge gaps and future directions. Sanjeev Kumar, Kelem Kassahun, Richard A. Tschirret-Guth, PubMed Pharmaceutical ResearchDrug TargetMetabolic ActivationLead IdentificationPharmaceutical Lead Optimization	2008	47
Discovery of spirocyclic secondary amine-derived tertiary ureas as highly potent, selective and bioavailable soluble epoxide hydrolase inhibitors Hong C. Shen, Fa‐Xiang Ding, Siyi Wang, Bioorganic & Medicinal Chemistry Letters Medicinal ChemistryBiochemistryNatural SciencesMedicineDrug Development	2009	42
Discovery of a Highly Potent, Selective, and Bioavailable Soluble Epoxide Hydrolase Inhibitor with Excellent Ex Vivo Target Engagement Hong C. Shen, Fa‐Xiang Ding, Siyi Wang, Journal of Medicinal Chemistry Lipid PeroxidationPharmacotherapyBenchmark 2DExperimental PharmacologyPharmaceutical Chemistry	2009	42
Structure-Based Design of an Iminoheterocyclic β-Site Amyloid Precursor Protein Cleaving Enzyme (BACE) Inhibitor that Lowers Central Aβ in Nonhuman Primates Mihirbaran Mandal, Yusheng Wu, Jeffrey Misiaszek, Journal of Medicinal Chemistry	2016	41
Application of a Rat Liver Drug Bioactivation Transcriptional Response Assay Early in Drug Development That Informs Chemically Reactive Metabolite Formation and Potential for Drug-induced Liver Injury James J Monroe, Keith Q. Tanis, Alexei A. Podtelezhnikov, Toxicological Sciences Systems BiologyDrug CandidatesBiochemistryPredictive ToxicologyMedicine	2020	31
AI/ML Models to Predict the Severity of Drug-Induced Liver Injury for Small Molecules Mohan Rao, Vahid Nassiri, Cristóbal Alhambra, Chemical Research in Toxicology	2023	30
Disruption of Gene Expression and Induction of Apoptosis in Prostate Cancer Cells by a DNA-Damaging Agent Tethered to an Androgen Receptor Ligand John C. Marquis, Shawn Hillier, A. Nicole Dinaut, Chemistry & Biology Androgen Receptor LigandOncogenic AgentApoptosisCell DeathProstate Cancer Cells	2005	29

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