Concepedia

Author

Sylvia Mahara

National University of SingaporeORCID

Also Known As

Sylvia Mahara

12

Publications

822

Citations

9

H-Index

26

Concepts

All Affiliations

National University of SingaporeNational University Cancer Institute, SingaporeGenome Institute of SingaporeInstitute of Molecular and Cell BiologyNational University Hospital
SM

About

Sylvia Mahara is an author at National University of Singapore specializing in tumor biology, cancer research, and cell biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

172

2

Cell Biology

3

3

172

3

Cancer Cell Biology

2

2

107

4

Natural Sciences

1

1

65

5

Cancer Genetics

1

1

65

Sylvia Mahara

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8

Publications

809

Citations

8

H-Index

YearCitations

Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer

Yen-An Tang, Yu-feng Chen, Bao Yi,

Proceedings of the National Academy of Sciences

2018

267

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML

Jianbiao Zhou, Chonglei Bi, Lip-Lee Cheong,

Blood

2011

210

HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer

Sylvia Mahara, Puay Leng Lee, Min Feng,

Proceedings of the National Academy of Sciences

2016

89

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

Jianbiao Zhou, Chonglei Bi, Wee Joo Chng,

PLoS ONE

2011

65

Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer

Chunhua Wan, Sylvia Mahara, Claire Sun,

Science Advances

2021

65

MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

Dhanya Sooraj, Claire Sun, Anh Doan,

Molecular Cell

2021

42

Aged intestinal stem cells propagate cell-intrinsic sources of inflammaging in mice

Maja C. Funk, Jan Gleixner, Florian Heigwer,

Developmental Cell

2023

39

The pro-metastasis tyrosine phosphatase, PRL-3 (PTP4A3), is a novel mediator of oncogenic function of BCR-ABL in human chronic myeloid leukemia

Jianbiao Zhou, Lip-Lee Cheong, Shaw-Cheng Liu,

Molecular Cancer

2012

32

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