Concepedia

Sylvia Mahara

SM

8

Publications

809

Citations

8

H-Index

2011

Active since

Affiliations

National University of Singapore(Current)

National University Cancer Institute, Singapore

Genome Institute of Singapore

Institute of Molecular and Cell Biology

National University Hospital

Sylvia Mahara is an author at National University of Singapore specializing in tumor biology, cancer research, and cell biology.

ORCID

Top concepts

Publications per year

2011–2023

8

Publications

8

Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer

Yen-An Tang, Yu-feng Chen, Bao Yi et al. · Proceedings of the National Academy of Sciences · 2018 · 267 citations · Full text

The histone methyltransferase inhibitor, DZNep, up-regulates TXNIP, increases ROS production, and targets leukemia cells in AML

Jianbiao Zhou, Chonglei Bi, Lip-Lee Cheong et al. · Blood · 2011 · 210 citations · Full text

HIFI-α activation underlies a functional switch in the paradoxical role of Ezh2/PRC2 in breast cancer

Sylvia Mahara, Puay Leng Lee, Min Feng et al. · Proceedings of the National Academy of Sciences · 2016 · 89 citations · Full text

PRL-3, a Metastasis Associated Tyrosine Phosphatase, Is Involved in FLT3-ITD Signaling and Implicated in Anti-AML Therapy

Jianbiao Zhou, Chonglei Bi, Wee Joo Chng et al. · PLoS ONE · 2011 · 65 citations · Full text

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Genome-scale CRISPR-Cas9 screen of Wnt/β-catenin signaling identifies therapeutic targets for colorectal cancer

Chunhua Wan, Sylvia Mahara, Claire Sun et al. · Science Advances · 2021 · 65 citations · Full text

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