Concepedia

Puay Leng Lee

PL

21

Publications

3.4K

Citations

20

H-Index

2007

Active since

Affiliations

Genome Institute of Singapore(Current)

National University of Singapore

Agency for Science, Technology and Research

Duke-NUS Medical School

Jinan University

Puay Leng Lee is an author at Genome Institute of Singapore specializing in cell biology, medicine, and tumor biology.

Top concepts

Publications per year

2007–2025

21

Publications

21

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

Jing Tan, Xiaojing Yang, Li Zhuang et al. · Genes & Development · 2007 · 894 citations · Full text

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer

L.S. Ong, Wee Chyan Lee, Shijun Ma et al. · Proceedings of the National Academy of Sciences · 2022 · 565 citations · Full text

Hypoxic tumor microenvironment activates GLI2 via HIF-1α and TGF-β2 to promote chemoresistance in colorectal cancer

Yen-An Tang, Yu-feng Chen, Bao Yi et al. · Proceedings of the National Academy of Sciences · 2018 · 267 citations · Full text

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in Colorectal Cancer and Is a Therapeutic Target of Histone Modifications

Xia Jiang, Jing Tan, Jingsong Li et al. · Cancer Cell · 2008 · 237 citations · Full text

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IRAK1 is a therapeutic target that drives breast cancer metastasis and resistance to paclitaxel

Zhen Ning Wee, Siti Maryam J. M. Yatim, Vera Kohlbauer et al. · Nature Communications · 2015 · 169 citations · Full text

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