Wee Chyan Lee

IFI16-dependent STING signaling is a crucial regulator of anti-HER2 immune response in HER2+ breast cancer

L.S. Ong, Wee Chyan Lee, Shijun Ma et al. · Proceedings of the National Academy of Sciences · 2022 · 567 citations · Full text

Life Sciences, Immunology, Oncology +17

Hypoxia induces HIF1α-dependent epigenetic vulnerability in triple negative breast cancer to confer immune effector dysfunction and resistance to anti-PD-1 immunotherapy

Shijun Ma, Yue Zhao, Wee Chyan Lee et al. · Nature Communications · 2022 · 175 citations · Full text

Life Sciences, Immunology, Oncology +17

Stromal induction of BRD4 phosphorylation Results in Chromatin Remodeling and BET inhibitor Resistance in Colorectal Cancer

Wenyu Wang, Yen‐An Tang, Qian Xiao et al. · Nature Communications · 2021 · 115 citations · Full text

Medicine, Cancer Biology, Oncology +16

EZH2-mediated PP2A inactivation confers resistance to HER2-targeted breast cancer therapy

Bao Yi, Gokce Oguz, Wee Chyan Lee et al. · Nature Communications · 2020 · 54 citations · Full text

Medicine, Molecular Biology, Oncology +17

Targeting P4HA1 promotes CD8+ T cell progenitor expansion toward immune memory and systemic anti-tumor immunity

Shijun Ma, L.S. Ong, Zemin Jiang et al. · Cancer Cell · 2024 · 38 citations

Life Sciences, Immunology, Oncology +12