Xia Jiang

Pharmacologic disruption of Polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells

Jing Tan, Xiaojing Yang, Li Zhuang et al. · Genes & Development · 2007 · 898 citations · Full text

Life Sciences, Genetics, Oncology +17

Methionine is a metabolic dependency of tumor-initiating cells

Zhenxun Wang, Lian Yee Yip, Jia Hui Jane Lee et al. · Nature Medicine · 2019 · 393 citations

Medicine, Cancer Biology, Oncology +14

<i>miR-449a</i> and <i>miR-449b</i> are direct transcriptional targets of E2F1 and negatively regulate pRb–E2F1 activity through a feedback loop by targeting <i>CDK6</i> and <i>CDC25A</i>

Xiaojing Yang, Min Feng, Xia Jiang et al. · Genes & Development · 2009 · 247 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Inhibitors of histone deacetylases target the Rb-E2F1 pathway for apoptosis induction through activation of proapoptotic protein Bim

Yan Zhao, Jing Tan, Li Zhuang et al. · Proceedings of the National Academy of Sciences · 2005 · 243 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

DACT3 Is an Epigenetic Regulator of Wnt/β-Catenin Signaling in Colorectal Cancer and Is a Therapeutic Target of Histone Modifications

Xia Jiang, Jing Tan, Jingsong Li et al. · Cancer Cell · 2008 · 238 citations · Full text

Medicine, Molecular Biology, Oncology +17