Taylor L. Mighell

A Saturation Mutagenesis Approach to Understanding PTEN Lipid Phosphatase Activity and Genotype-Phenotype Relationships

Taylor L. Mighell, Sara Evans-Dutson, Brian J. O’Roak · The American Journal of Human Genetics · 2018 · 222 citations · Full text

Signal Transduction, Biochemistry, Natural Sciences +7

AAV-Mediated CRISPR/Cas9 Gene Editing in Murine Phenylketonuria

Daelyn Y. Richards, Shelley R. Winn, Sandra Dudley et al. · Molecular Therapy — Methods & Clinical Development · 2019 · 91 citations · Full text

An Integrated Deep-Mutational-Scanning Approach Provides Clinical Insights on PTEN Genotype-Phenotype Relationships

Taylor L. Mighell, Stetson Thacker, Éric Fombonne et al. · The American Journal of Human Genetics · 2020 · 55 citations · Full text

Pten Genotype-phenotype Relationships, Medicine, Genetics +6

A Sort-Seq Approach to the Development of Single Fluorescent Protein Biosensors

John N. Koberstein, Melissa L. Stewart, Taylor L. Mighell et al. · ACS Chemical Biology · 2021 · 18 citations · Full text

Engineering, Biomolecular Tool, Gfp Insertion +18

SUNi mutagenesis: Scalable and uniform nicking for efficient generation of variant libraries

Taylor L. Mighell, Ignasi Toledano, Ben Lehner · PLoS ONE · 2023 · 14 citations · Full text