Wouter Beumer

Splice-Modulating Oligonucleotide QR-110 Restores CEP290 mRNA and Function in Human c.2991+1655A>G LCA10 Models

Kalyan Dulla, Mònica Aguilà, Amelia Lane et al. · Molecular Therapy — Nucleic Acids · 2018 · 162 citations · Full text

G Lca10 Models, Transcriptional Regulation, Natural Sciences +8

Antisense oligonucleotide-based treatment of retinitis pigmentosa caused by USH2A exon 13 mutations

Kalyan Dulla, Ralph Slijkerman, Hester C. van Diepen et al. · Molecular Therapy · 2021 · 135 citations · Full text

Antisense oligonucleotide therapy corrects splicing in the common Stargardt disease type 1-causing variant ABCA4 c.5461-10T>C

Melita Kaltak, Petra de Bruijn, Davide Piccolo et al. · Molecular Therapy — Nucleic Acids · 2023 · 38 citations · Full text

Improving Translation by Identifying Evidence for More Human-Relevant Preclinical Strategies

Merel Ritskes‐Hoitinga, Cathalijn H. C. Leenaars, Wouter Beumer et al. · Animals · 2020 · 25 citations · Full text

Translation Studies, Multilingualism, Translational Advance +17

Evaluation of eluforsen, a novel RNA oligonucleotide for restoration of CFTR function in in vitro and murine models of p.Phe508del cystic fibrosis

Wouter Beumer, Jim Swildens, Teresinha Leal et al. · PLoS ONE · 2019 · 24 citations · Full text

Inflammatory Lung Disease, Molecular Biology, Cellular Physiology +17