Ian Powley

Co-operative and Hierarchical Binding of c-FLIP and Caspase-8: A Unified Model Defines How c-FLIP Isoforms Differentially Control Cell Fate

Michelle A. Hughes, Ian Powley, Rebekah Jukes‐Jones et al. · Molecular Cell · 2016 · 250 citations · Full text

Death Receptor-induced Apoptosis, Apoptosis, Molecular Biology +17

Translational reprogramming following UVB irradiation is mediated by DNA-PKcs and allows selective recruitment to the polysomes of mRNAs encoding DNA repair enzymes

Ian Powley, Alexander Kondrashov, Lucy A. Young et al. · Genes & Development · 2009 · 142 citations · Full text

Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a ( Ink4a/Arf )

Tatyana Chernova, Fiona Murphy, Sara Galavotti et al. · Current Biology · 2017 · 135 citations · Full text

Cryo-EM structural analysis of FADD:Caspase-8 complexes defines the catalytic dimer architecture for co-ordinated control of cell fate

Joanna L. Fox, Michelle A. Hughes, Xin Meng et al. · Nature Communications · 2021 · 63 citations · Full text

Molecular profiling reveals primary mesothelioma cell lines recapitulate human disease

Tatiana A. Chernova, Xiaoming Sun, Ian Powley et al. · Cell Death and Differentiation · 2016 · 56 citations · Full text

Tumor Biology, Oncology, Glioma +13