David J. Richard

ATP-Competitive Inhibitors of the Mammalian Target of Rapamycin: Design and Synthesis of Highly Potent and Selective Pyrazolopyrimidines

Arie Zask, Jeroen C. Verheijen, Kevin J. Curran et al. · Journal of Medicinal Chemistry · 2009 · 98 citations · Full text

Chemical Biology, Pharmaceutical Chemistry, Tumor Biology +19

Morpholine Derivatives Greatly Enhance the Selectivity of Mammalian Target of Rapamycin (mTOR) Inhibitors

Arie Zask, Joshua A. Kaplan, Jeroen C. Verheijen et al. · Journal of Medicinal Chemistry · 2009 · 96 citations · Full text

Drug Target, Bioorganic Chemistry, Pharmacotherapy +17

Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): Optimization of the 1-substituent

Kevin J. Curran, Jeroen C. Verheijen, Joshua A. Kaplan et al. · Bioorganic & Medicinal Chemistry Letters · 2010 · 63 citations · Full text

Medicinal Chemistry, Mammalian Target, Drug Target +12

Total Synthesis of Isoroquefortine C

Bruno Schiavi, David J. Richard, Madeleine M. Joullié · The Journal of Organic Chemistry · 2001 · 59 citations

Medicinal Chemistry, Isoroquefortine C, Natural Sciences +9

Hydroxyquinoline-derived compounds and analoguing of selective Mcl-1 inhibitors using a functional biomarker

David J. Richard, Ryan Lena, Thomas D. Bannister et al. · Bioorganic & Medicinal Chemistry · 2013 · 54 citations · Full text

Medicinal Chemistry, Biochemistry, Medicine +9