Adrie Jones

Stimulus-Specific Effects of Pentoxifylline on Neutrophil CR3 Expression, Degranulation, and Superoxide Production

Mark S. Currie, K. Murali Krishna Rao, Jaya Padmanabhan et al. · Journal of Leukocyte Biology · 1990 · 85 citations

A Homogeneous Enzyme Fragment Complementation-Based β-Arrestin Translocation Assay for High-Throughput Screening of G-Protein-Coupled Receptors

Xiaoning Zhao, Adrie Jones, Keith R. Olson et al. · SLAS DISCOVERY · 2008 · 78 citations · Full text

Discovery of selective biaryl ethers as PDE10A inhibitors: Improvement in potency and mitigation of Pgp-mediated efflux

Robert M. Rzasa, Essa Hu, Shannon Rumfelt et al. · Bioorganic & Medicinal Chemistry Letters · 2012 · 26 citations · Full text

Medicinal Chemistry, Biochemistry, Selective Biaryl Ethers +10

Discovery and in Vivo Evaluation of Macrocyclic Mcl-1 Inhibitors Featuring an α-Hydroxy Phenylacetic Acid Pharmacophore or Bioisostere

Gwenaëlla Rescourio, Ana Z. González, Salman Jabri et al. · Journal of Medicinal Chemistry · 2019 · 24 citations

Potent Mcl-1 Inhibitor, Chemoprevention Strategy, Pharmacotherapy +25

Synthesis and preliminary biological evaluation of potent and selective 2-(3-alkoxy-1-azetidinyl) quinolines as novel PDE10A inhibitors with improved solubility

Robert M. Rzasa, Michael Frohn, Kristin L. Andrews et al. · Bioorganic & Medicinal Chemistry · 2014 · 18 citations · Full text

Medicinal Chemistry, Preliminary Biological Evaluation, Biochemistry +10