Ion Niculescu‐Duvaz

<i>RAS</i> Mutations in Cutaneous Squamous-Cell Carcinomas in Patients Treated with BRAF Inhibitors

Fei Su, Amaya Virós, Carla Milagre et al. · New England Journal of Medicine · 2012 · 1K citations · Full text

Medicine, Dermatology, Oncology +13

Nilotinib and MEK Inhibitors Induce Synthetic Lethality through Paradoxical Activation of RAF in Drug-Resistant Chronic Myeloid Leukemia

Leisl Packer, Sareena Rana, Robert Hayward et al. · Cancer Cell · 2011 · 125 citations · Full text

Medicine, Oncology, Pharmacology +14

Optimization of Alkylating Agent Prodrugs Derived from Phenol and Aniline Mustards: A New Clinical Candidate Prodrug (ZD2767) for Antibody-Directed Enzyme Prodrug Therapy

Caroline J. Springer, Robert I. Dowell, D C Blakey et al. · Journal of Medicinal Chemistry · 1995 · 90 citations

Pharmacy, Medicinal Chemistry, Pharmacology +15

Primary Melanoma of the CNS in Children Is Driven by Congenital Expression of Oncogenic <i>NRAS</i> in Melanocytes

Malin Pedersen, Heidi V.N. Küsters‐Vandevelde, Amaya Virós et al. · Cancer Discovery · 2013 · 78 citations · Full text

Medicine, Developmental Biology, Oncology +17

Trastuzumab emtansine, an antibody-drug conjugate for the treatment of HER2+ metastatic breast cancer.

Ion Niculescu‐Duvaz · PubMed · 2010 · 64 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17