Ivan J. Stone

SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

May S.K. Sutherland, Roland B. Walter, Scott C. Jeffrey et al. · Blood · 2013 · 381 citations

A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology

Scott C. Jeffrey, Patrick Burke, Robert P. Lyon et al. · Bioconjugate Chemistry · 2013 · 241 citations

Drug Target, Immunology, Molecular Biology +21

Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment

Charlotte F. McDonagh, Eileen Turcott, Lori Westendorf et al. · Protein Engineering Design and Selection · 2006 · 236 citations · Full text

Medicinal Chemistry, Parental Antibody-drug Conjugates, Medicine +15

Development and Properties of β-Glucuronide Linkers for Monoclonal Antibody−Drug Conjugates

Scott C. Jeffrey, Jamie B. Andreyka, Starr X. Bernhardt et al. · Bioconjugate Chemistry · 2006 · 166 citations

Immunology, Glycobiology, Mmaf Conjugate C1f6-9b +16

Optimization of a PEGylated Glucuronide-Monomethylauristatin E Linker for Antibody–Drug Conjugates

Patrick Burke, Joseph Z. Hamilton, Scott C. Jeffrey et al. · Molecular Cancer Therapeutics · 2016 · 142 citations