SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

May S.K. Sutherland, Roland B. Walter, Scott C. Jeffrey, +17

Blood

Engineered antibody-drug conjugates with defined sites and stoichiometries of drug attachment

Charlotte F. McDonagh, Eileen Turcott, Lori Westendorf, +8

Protein Engineering Design and Selection

Medicinal ChemistryParental Antibody-drug ConjugatesMedicineDrug DiscoveryDrug Attachment +13

Development of orally active inhibitors of protein and cellular fucosylation

Nicole M. Okeley, Stephen C. Alley, Martha E. Anderson, +13

Proceedings of the National Academy of Sciences

Vitro FucosylationGlycobiologyImmunologyImmunotherapyTumor Biology +19

SGN–LIV1A: A Novel Antibody–Drug Conjugate Targeting LIV-1 for the Treatment of Metastatic Breast Cancer

Django Sussman, Leia M. Smith, Martha E. Anderson, +9

Molecular Cancer Therapeutics

Metastatic Breast CancerBreast OncologyDrug TargetingNovel Antibody-drug ConjugateImmunology +9

Engineered anti-CD70 antibody-drug conjugate with increased therapeutic index

Charlotte F. McDonagh, Kristine M. Kim, Eileen Turcott, +11

Molecular Cancer Therapeutics

Characterization of SGN-CD123A, A Potent CD123-Directed Antibody–Drug Conjugate for Acute Myeloid Leukemia

Fu Li, May Kung Sutherland, Changpu Yu, +19

Molecular Cancer Therapeutics

Anti-CD30 diabody-drug conjugates with potent antitumor activity

Kristine M. Kim, Charlotte F. McDonagh, Lori Westendorf, +11

Molecular Cancer Therapeutics

A major role for zygotic<i>hunchback</i>in patterning the<i>Nasonia</i>embryo

Mary Anne Pultz, Lori Westendorf, Samuel D. Gale, +8

Development

Tumor-Associated Macrophages Can Contribute to Antitumor Activity through FcγR-Mediated Processing of Antibody–Drug Conjugates

Fu Li, Michelle Ulrich, Mechthild Jonas, +6

Molecular Cancer Therapeutics

Suppression subtractive hybridization and expression profiling identifies a unique set of genes overexpressed in non-small-cell lung cancer

Joseph M. Petroziello, Andrew K. Yamane, Lori Westendorf, +6

Oncogene

Functional GenomicsTumor HeterogeneityMedicineGeneticsCancer Genomics +12