Django Sussman

SGN-CD33A: a novel CD33-targeting antibody–drug conjugate using a pyrrolobenzodiazepine dimer is active in models of drug-resistant AML

May S.K. Sutherland, Roland B. Walter, Scott C. Jeffrey et al. · Blood · 2013 · 386 citations

Pharmacy, Oncology, Pharmacology +13

Computational redesign of endonuclease DNA binding and cleavage specificity

J. R. Ashworth, James J. Havranek, Carlos M. Duarte et al. · Nature · 2006 · 343 citations · Full text

Life Sciences, Bioinformatics, Molecular Biology +16

A Potent Anti-CD70 Antibody–Drug Conjugate Combining a Dimeric Pyrrolobenzodiazepine Drug with Site-Specific Conjugation Technology

Scott C. Jeffrey, Patrick Burke, Robert P. Lyon et al. · Bioconjugate Chemistry · 2013 · 246 citations

Pharmacy, Oncology, Pharmacology +17

Development of orally active inhibitors of protein and cellular fucosylation

Nicole M. Okeley, Stephen C. Alley, Martha E. Anderson et al. · Proceedings of the National Academy of Sciences · 2013 · 192 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

Structural Basis of Microtubule Destabilization by Potent Auristatin Anti-Mitotics

Andrew B. Waight, Katja Bargsten, Svetlana Doronina et al. · PLoS ONE · 2016 · 165 citations · Full text

Medicine, Medicinal Chemistry, Oncology +15