A novel multiple-stage antimalarial agent that inhibits protein synthesis

Beatriz Baragaña, Irene Hallyburton, Neil R. Norcross, +60

Nature

Antiparasitic AgentMedicineMalariaPharmacologyProtein Synthesis +2

Human TLR10 is an anti-inflammatory pattern-recognition receptor

Marije Oosting, Shih‐Chin Cheng, Judith M. Bolscher, +13

Proceedings of the National Academy of Sciences

Antimalarial pantothenamide metabolites target acetyl–coenzyme A biosynthesis in <i>Plasmodium falciparum</i>

Joost Schalkwijk, Erik L. Allman, Patrick A.M. Jansen, +28

Science Translational Medicine

A combination of new screening assays for prioritization of transmission-blocking antimalarials reveals distinct dynamics of marketed and experimental drugs

Judith M. Bolscher, Karin M. J. Koolen, Geert Jan van Gemert, +5

Journal of Antimicrobial Chemotherapy

Analysis of a Multi-component Multi-stage Malaria Vaccine Candidate—Tackling the Cocktail Challenge

Alexander Boes, Holger Spiegel, Nadja Voepel, +14

PLoS ONE

Highly potent, naturally acquired human monoclonal antibodies against Pfs48/45 block Plasmodium falciparum transmission to mosquitoes

Amanda Fabra-García, Sophia Hailemariam, Roos M. de Jong, +25

Immunity

Preclinical characterization and target validation of the antimalarial pantothenamide MMV693183

Laura E. de Vries, Patrick A.M. Jansen, Catalina Barceló, +42

Nature Communications

Potent transmission-blocking monoclonal antibodies from naturally exposed individuals target a conserved epitope on Plasmodium falciparum Pfs230

Danton Ivanochko, Amanda Fabra-García, Karina Teelen, +22

Immunity

The Plasmodium falciparum circumsporozoite protein produced in Lactococcus lactis is pure and stable

Susheel Kumar Singh, Jordan Plieskatt, Bishwanath Kumar Chourasia, +9

Journal of Biological Chemistry

A P. falciparum NF54 Reporter Line Expressing mCherry-Luciferase in Gametocytes, Sporozoites, and Liver-Stages

Catherin Marin-Mogollon, Ahmed M. Salman, Karin M. J. Koolen, +15

Frontiers in Cellular and Infection Microbiology