Concepedia

Author

Sorcha O’Byrne

University of OxfordORCID

Also Known As

Natalina Elliot, O'Byrne S., O'Byrne, Sorcha I, S. O’Byrne, Sophie F. Monks O’Byrne, Sorcha I O'Byrne, Sorcha Isabella O'Byrne, Sorcha O'Byrne, Sorcha O’Byrne

25

Publications

653

Citations

10

H-Index

24

Concepts

All Affiliations

University of OxfordMRC Weatherall Institute of Molecular MedicineOxford BioMedica (United Kingdom)Imperial College LondonJohn Radcliffe Hospital
SO

About

Sorcha O’Byrne is an author at University of Oxford specializing in medicine, hematology, and cell biology.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

3

3

270

2

Cell Biology

2

2

125

3

Immunology

2

2

179

4

Cellular Therapies

1

1

34

5

Autoimmune Disease

1

1

145

Sorcha O’Byrne

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9

Publications

621

Citations

9

H-Index

YearCitations

Blood and immune development in human fetal bone marrow and Down syndrome

Laura Jardine, Simone Webb, Issac Goh,

Nature

2021

145

Discovery of a CD10-negative B-progenitor in human fetal life identifies unique ontogeny-related developmental programs

Sorcha O’Byrne, Natalina Elliott, Siobhan Rice,

Blood

2019

92

MLL-AF4 Spreading Identifies Binding Sites that Are Distinct from Super-Enhancers and that Govern Sensitivity to DOT1L Inhibition in Leukemia

Jon Kerry, Laura Godfrey, Emmanouela Repapi,

Cell Reports

2017

91

Transitions in lineage specification and gene regulatory networks in hematopoietic stem/progenitor cells over human development

Anindita Roy, Guanlin Wang, Deena Iskander,

Cell Reports

2021

87

H3K79me2/3 controls enhancer–promoter interactions and activation of the pan-cancer stem cell marker PROM1/CD133 in MLL-AF4 leukemia cells

Laura Godfrey, Nicholas T. Crump, Sorcha O’Byrne,

Leukemia

2020

63

A human fetal liver-derived infant MLL-AF4 acute lymphoblastic leukemia model reveals a distinct fetal gene expression program

Siobhan Rice, Thomas Jackson, Nicholas T. Crump,

Nature Communications

2021

49

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

Eleni Louka, Benjamin Povinelli, Alba Rodríguez-Meira,

IRIS UNIMORE (University of Modena and Reggio Emilia)

2021

41

CD34+CD19−CD22+ B-cell progenitors may underlie phenotypic escape in patients treated with CD19-directed therapies

Clara Bueno, Susana Barrera, Álex Bataller,

Blood

2022

34

High resolution IgH repertoire analysis reveals fetal liver as the likely origin of life-long, innate B lymphopoiesis in humans

Anindita Roy, Vojtěch Bystrý, Georg Bohn,

Clinical Immunology

2017

19

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