Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss

Anne L. Spieles-Engemann, Michael M. Behbehani, Timothy J. Collier, +10

Neurobiology of Disease

Health SciencesNeurophysiologyNeuroanatomyPhysiologyNeurotransmitter +10

Subthalamic Nucleus Stimulation Increases Brain Derived Neurotrophic Factor in the Nigrostriatal System and Primary Motor Cortex

Anne L. Spieles-Engemann, Kathy Steece‐Collier, Michael M. Behbehani, +9

Journal of Parkinson s Disease

Morphological and Behavioral Impact of AAV2/5-Mediated Overexpression of Human Wildtype Alpha-Synuclein in the Rat Nigrostriatal System

Sara E. Gombash, Fredric P. Manfredsson, Christopher J. Kemp, +7

PLoS ONE

Subthalamic nucleus stimulation increases brain derived neurotrophic factor in the nigrostriatal system and primary motor cortex.

Anne L. Spieles-Engemann, Kathy Steece‐Collier, Michael M. Behbehani, +9

PubMed

Unilateral Stn DbsPrimary Motor CortexSocial SciencesNigrostriatal SystemNeurobiology Of Disease +18

SMN expression is required in motor neurons to rescue electrophysiological deficits in the SMNΔ7 mouse model of SMA

Vicki L. McGovern, Chitra C. Iyer, W. David Arnold, +5

Human Molecular Genetics

Muscle FunctionGeneticsSmnδ7 Mouse ModelNeurotransmissionCellular Neurobiology +23

SMN deficiency disrupts gastrointestinal and enteric nervous system function in mice

Sara E. Gombash, Christopher Cowley, Julie C. Fitzgerald, +8

Human Molecular Genetics

GastroenterologyPathologyDigestive TractPeripheral Nervous SystemGastrointestinal Peptide Hormone +17

Intravenous AAV9 efficiently transduces myenteric neurons in neonate and juvenile mice

Sara E. Gombash, Christopher Cowley, Julie C. Fitzgerald, +4

Frontiers in Molecular Neuroscience

Myenteric NeuronsGastroenterologyPathologyTherapeuticsJuvenile Mice +15

Low levels of Survival Motor Neuron protein are sufficient for normal muscle function in the SMNΔ7 mouse model of SMA

Chitra C. Iyer, Vicki L. McGovern, Jason D. Murray, +5

Human Molecular Genetics

Muscle FunctionGeneticsSmnδ7 Mouse ModelCytoskeletonLow Levels +20

Striatal Pleiotrophin Overexpression Provides Functional and Morphological Neuroprotection in the 6-Hydroxydopamine Model

Sara E. Gombash, Jack W. Lipton, Timothy J. Collier, +11

Molecular Therapy

Neuroprotective potential of pleiotrophin overexpression in the striatonigral pathway compared with overexpression in both the striatonigral and nigrostriatal pathways

Sara E. Gombash, Fredric P. Manfredsson, Ronald J. Mandel, +7

Gene Therapy

Striatonigral PathwayNeurophysiologyNeuroanatomyPhysiologyNeurotransmitter +12