A novel cell-cycle-indicator, mVenus-p27K−, identifies quiescent cells and visualizes G0–G1 transition

Toshihiko Oki, Koutarou Nishimura, Jiro Kitaura, +10

Scientific Reports

Myelodysplastic syndromes are induced by histone methylation–altering ASXL1 mutations

Daichi Inoue, Jiro Kitaura, Katsuhiro Togami, +21

Journal of Clinical Investigation

Histone ModificationsMds PathogenesisMixed-phenotype Acute LeukemiaGeneticsEpigenetic Change +22

The Receptor LMIR3 Negatively Regulates Mast Cell Activation and Allergic Responses by Binding to Extracellular Ceramide

Kumi Izawa, Yoshinori Yamanishi, Akie Maehara, +13

Immunity

InflammationMolecular PhysiologyAllergySignal TransductionExtracellular Ceramide +10

Ceramide-CD300f binding suppresses experimental colitis by inhibiting ATP-mediated mast cell activation

Toshihiro Matsukawa, Kumi Izawa, Masamichi Isobe, +8

Gut

An Activating and Inhibitory Signal from an Inhibitory Receptor LMIR3/CLM-1: LMIR3 Augments Lipopolysaccharide Response through Association with FcRγ in Mast Cells

Kumi Izawa, Jiro Kitaura, Yoshinori Yamanishi, +9

The Journal of Immunology

Mast Cell DisorderImmunologyImmune RegulationImmunologic MechanismImmune System +17

Ceramide-CD300f Binding Inhibits Lipopolysaccharide-induced Skin Inflammation

Emiko Shiba, Kumi Izawa, Ayako Kaitani, +10

Journal of Biological Chemistry

A Soluble Form of LMIR5/CD300b Amplifies Lipopolysaccharide-Induced Lethal Inflammation in Sepsis

Yoshinori Yamanishi, Mariko Takahashi, Kumi Izawa, +14

The Journal of Immunology

Acute Lung InjuryImmunologyRenal InflammationImmune RegulationImmunologic Mechanism +17

Human CD300C Delivers an Fc Receptor-γ-dependent Activating Signal in Mast Cells and Monocytes and Differs from CD300A in Ligand Recognition

Mariko Takahashi, Kumi Izawa, Jun‐ichi Kashiwakura, +14

Journal of Biological Chemistry

Aberrant expression of RasGRP1 cooperates with gain-of-function NOTCH1 mutations in T-cell leukemogenesis

Toshihiko Oki, Jiro Kitaura, Naoko Watanabe‐Okochi, +9

Leukemia

Rasgrp1 CooperatesLymphocyte DevelopmentAberrant ExpressionT-cell LeukemogenesisImmunology +7

Disrupting ceramide-CD300f interaction prevents septic peritonitis by stimulating neutrophil recruitment

Kumi Izawa, Akie Maehara, Masamichi Isobe, +25

Scientific Reports