Tom Hassell

2′-OMe-phosphorodithioate-modified siRNAs show increased loading into the RISC complex and enhanced anti-tumour activity

Sherry Y. Wu, Xianbin Yang, Kshipra M. Gharpure et al. · Nature Communications · 2014 · 132 citations · Full text

Medicinal Chemistry, Drug Targeting, Biochemistry +10

Safety and antiviral activity of triple combination broadly neutralizing monoclonal antibody therapy against HIV-1: a phase 1 clinical trial

Boris Jülg, Kathryn E. Stephenson, Kshitij Wagh et al. · Nature Medicine · 2022 · 128 citations · Full text

Evoking picomolar binding in RNA by a single phosphorodithioate linkage

Nalin Abeydeera, Martin Egli, Nehemiah Cox et al. · Nucleic Acids Research · 2016 · 119 citations · Full text

Rna Aptamers, Molecular Biology, Molecular Genetics +23

Process development for the production of recombinant antibodies using the glutamine synthetase (GS) system

M. E. Brown, G. Renner, Ray Field et al. · Cytotechnology · 1992 · 92 citations

Biosynthesis, Engineering, Biochemistry +11

Dual Roles for Lipolysis and Oxidation in Peroxisome Proliferation-Activator Receptor Responses to Electronegative Low Density Lipoprotein

Ouliana Ziouzenkova, Liana Asatryan, Deanna Sahady et al. · Journal of Biological Chemistry · 2003 · 63 citations · Full text

Oxysterol, Biochemistry, Lipid Peroxidation +9