Philip H. Howe

A regulated PNUTS mRNA to lncRNA splice switch mediates EMT and tumour progression

Simon Grelet, Laura A. Link, Breege V. Howley et al. · Nature Cell Biology · 2017 · 394 citations · Full text

Engineering, Rna Splicing, Rna Biology +9

TGF-β-mediated phosphorylation of hnRNP E1 induces EMT via transcript-selective translational induction of Dab2 and ILEI

Arindam Chaudhury, George S. Hussey, Partho Sarothi Ray et al. · Nature Cell Biology · 2010 · 305 citations · Full text

Transcriptional Regulation, Signal Transduction, Translational Biology +11

Evidence That Ser87 of BimEL Is Phosphorylated by Akt and Regulates BimEL Apoptotic Function

Xiaojun Qi, Gary Wildey, Philip H. Howe · Journal of Biological Chemistry · 2005 · 230 citations · Full text

Inflammation, Signal Transduction, Signaling Pathway +15

Transforming growth factor beta 1 inhibition of p34cdc2 phosphorylation and histone H1 kinase activity is associated with G1/S-phase growth arrest.

Philip H. Howe, Giulio Draetta, Edward B. Leof · Molecular and Cellular Biology · 1991 · 198 citations · Full text

P34cdc2 Phosphorylation, P34cdc2 Protein Kinase, Cell Proliferation +17

Identification of an mRNP Complex Regulating Tumorigenesis at the Translational Elongation Step

George S. Hussey, Arindam Chaudhury, Andrea E. Dawson et al. · Molecular Cell · 2011 · 188 citations · Full text

Chromatin, Transcriptional Regulation, Systems Biology +10