Edward B. Leof

Induction of c-sis mRNA and activity similar to platelet-derived growth factor by transforming growth factor beta: a proposed model for indirect mitogenesis involving autocrine activity.

Edward B. Leof, Jacqueline A. Proper, Anton Scott Goustin et al. · Proceedings of the National Academy of Sciences · 1986 · 538 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +12

Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis

Craig Daniels, Mark C. Wilkes, Maryanne Edens et al. · Journal of Clinical Investigation · 2004 · 525 citations · Full text

Life Sciences, Cell Biology, Pharmacotherapy +16

Imatinib mesylate inhibits the profibrogenic activity of TGF-β and prevents bleomycin-mediated lung fibrosis

Craig Daniels, Mark C. Wilkes, Maryanne Edens et al. · Journal of Clinical Investigation · 2004 · 486 citations · Full text

Life Sciences, Cell Biology, Pharmacotherapy +16

Imatinib mesylate blocks a non‐Smad TGF‐β pathway and reduces renal fibrogenesis in vivo

Shinong Wang, Mark C. Wilkes, Edward B. Leof et al. · The FASEB Journal · 2005 · 462 citations

Medicine, Nephrology, Pathology +17

Suramin inhibition of growth factor receptor binding and mitogenicity in AKR‐2B cells

Robert J. Coffey, Edward B. Leof, Gary D. Shipley et al. · Journal of Cellular Physiology · 1987 · 380 citations

Life Sciences, Cell Biology, Pharmacology +14