Ruud Delwel

Leukemic IDH1 and IDH2 Mutations Result in a Hypermethylation Phenotype, Disrupt TET2 Function, and Impair Hematopoietic Differentiation

María E. Figueroa, Omar Abdel‐Wahab, Chao Lü et al. · Cancer Cell · 2010 · 2.7K citations · Full text

Hematological Malignancy, Somatic Variant, Hypermethylation Phenotype +10

Inhibition of BET recruitment to chromatin as an effective treatment for MLL-fusion leukaemia

Mark A. Dawson, Rab K. Prinjha, Antje Dittmann et al. · Nature · 2011 · 1.5K citations · Full text

Hematological Malignancy, Chromatin, Bet Recruitment +11

Prognostically Useful Gene-Expression Profiles in Acute Myeloid Leukemia

Peter J.M. Valk, Roel G.W. Verhaak, M. Antoinette Beijen et al. · New England Journal of Medicine · 2004 · 1.4K citations · Full text

DNA Methylation Signatures Identify Biologically Distinct Subtypes in Acute Myeloid Leukemia

María E. Figueroa, Sanne Lugthart, Yushan Li et al. · Cancer Cell · 2010 · 826 citations · Full text

Hematological Malignancy, Chromatin, Epigenetic Change +10

A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia

Stefan Gröschel, Mathijs A. Sanders, Remco M. Hoogenboezem et al. · Cell · 2014 · 696 citations · Full text

Chromatin, Genetics, Gata2 Deregulation +6