Sachihiko Ozawa

Decreased expression of t-SNARE, syntaxin 1, and SNAP-25 in pancreatic beta-cells is involved in impaired insulin secretion from diabetic GK rat islets: restoration of decreased t-SNARE proteins improves impaired insulin secretion.

Shinya Nagamatsu, Yoko Nakamichi, Chie Yamamura et al. · Diabetes · 1999 · 173 citations

Immunology, Syntaxin 1, Cellular Physiology +16

Pioglitazone improves insulin secretory capacity and prevents the loss of β-cell mass in obese diabetic db/db mice: possible protection of β cells from oxidative stress

Hitoshi Ishida, Makoto Takizawa, Sachihiko Ozawa et al. · Metabolism · 2004 · 139 citations

Obesity, Metabolic Syndrome, Insulin Signaling +15

Activators of AMP-activated protein kinase enhance GLUT4 translocation and its glucose transport activity in 3T3-L1 adipocytes

Shinya Yamaguchi, Hiroshi Katahira, Sachihiko Ozawa et al. · American Journal of Physiology-Endocrinology and Metabolism · 2005 · 136 citations

Green Fluorescent Protein, Glucose Uptake, Cellular Physiology +18

PPAR-γ overexpression selectively suppresses insulin secretory capacity in isolated pancreatic islets through induction of UCP-2 protein

Eisuke Ito, Sachihiko Ozawa, Kazuto Takahashi et al. · Biochemical and Biophysical Research Communications · 2004 · 48 citations

Molecular Physiology, Signal Transduction, Insulin Management +11

Adenovirus‐mediated preproinsulin gene transfer into adipose tissues ameliorates hyperglycemia in obese diabetic KKA^y mice

Shinya Nagamatsu, Yoko Nakamichi, Mica Ohara‐Imaizumi et al. · FEBS Letters · 2001 · 30 citations