John P. Caldwell

Protecting group free radical C–H trifluoromethylation of peptides

Naoko Ichiishi, John P. Caldwell, Melissa Lin et al. · Chemical Science · 2018 · 126 citations · Full text

Aryl C-h Bonds, Engineering, Biochemistry +12

From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9

Whitney L. Petrilli, Gregory C. Adam, Roman S. Erdmann et al. · Cell chemical biology · 2019 · 80 citations · Full text

Biochemistry, Medicine, Natural Sciences +9

Design and Validation of Bicyclic Iminopyrimidinones As Beta Amyloid Cleaving Enzyme-1 (BACE1) Inhibitors: Conformational Constraint to Favor a Bioactive Conformation

Mihirbaran Mandal, Zhaoning Zhu, Jared N. Cumming et al. · Journal of Medicinal Chemistry · 2012 · 56 citations · Full text

Combinatorial Chemistry, Bicyclic Iminopyrimidinones, Pseudoaxial Conformation +21

The discovery and synthesis of novel adenosine receptor (A2A) antagonists

Julius J. Matasi, John P. Caldwell, Jinsong Hao et al. · Bioorganic & Medicinal Chemistry Letters · 2005 · 43 citations

Biochemistry, Functional Selectivity, Medicine +8

Structure-genotoxicity relationships of allylbenzenes and propenylbenzenes: A quantum chemical study

Ruey Shiuan Tsai, Pierre Alain Carrupt, Bernard Testa et al. · Chemical Research in Toxicology · 1994 · 42 citations