Martha A. Warpehoski

3-Aminopyrazole Inhibitors of CDK2/Cyclin A as Antitumor Agents. 1. Lead Finding

Paolo Pevarello, Maria Gabriella Brasca, Raffaella Amici et al. · Journal of Medicinal Chemistry · 2004 · 157 citations · Full text

Drug Target, Lead Identification, Pharmacotherapy +23

Molecular basis for sequence-specific DNA alkylation by CC-1065

Laurence H. Hurley, Chong Soon Lee, J. Patrick McGovren et al. · Biochemistry · 1988 · 143 citations

Stereoelectronic factors influencing the biological activity and DNA interaction of synthetic antitumor agents modeled on CC-1065

Martha A. Warpehoski, Ilse Gebhard, Robert C. Kelly et al. · Journal of Medicinal Chemistry · 1988 · 129 citations

Combinatorial Chemistry, Bioorganic Chemistry, Chemoprevention Strategy +18

Sequence specificity of DNA alkylation by the unnatural enantiomer of CC-1065 and its synthetic analogs

Laurence H. Hurley, Martha A. Warpehoski, Chong Soon Lee et al. · Journal of the American Chemical Society · 1990 · 106 citations

Bioorganic Chemistry, Engineering, Dna Analysis +21

Adozelesin, a selected lead among cyclopropylpyrroloindole analogs of the DNA-binding antibiotic, CC-1065

Li H. Li, Robert C. Kelly, Martha A. Warpehoski et al. · Investigational New Drugs · 1991 · 84 citations

Medicinal Chemistry, Bioorganic Chemistry, Biochemistry +12