Concepedia

Sebastian H. B. Kroll

SH

Statistics

Publications

8

Citations

553

H-Index

8

Active since

2009

Affiliations

Imperial College London(Current)

Hammersmith Hospital

Emory University

Sebastian H. B. Kroll is an author at Imperial College London specializing in cell cycle, drug discovery, and molecular dynamics.

Top concepts

Publications per year

2009–2024

8

Publications

8

The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity

Simak Ali, Dean A. Heathcote, Sebastian H. B. Kroll et al. · Cancer Research · 2009 · 162 citations · Full text

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Hetal Patel, Manikandan Periyasamy, Georgina P. Sava et al. · Molecular Cancer Therapeutics · 2018 · 138 citations · Full text

A Novel Pyrazolo[1,5-<i>a</i>]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration

Dean A. Heathcote, Hetal Patel, Sebastian H. B. Kroll et al. · Journal of Medicinal Chemistry · 2010 · 99 citations · Full text

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Victoria I. Cushing, Fujiet Koh, Junjie Feng et al. · Nature Communications · 2024 · 43 citations · Full text

Inhibitor Selectivity for Cyclin‐Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study

Pascale Hazel, Sebastian H. B. Kroll, Alexander Bondke et al. · ChemMedChem · 2017 · 40 citations

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