Sebastian H. B. Kroll

Statistics

Publications

Citations

564

H-Index

Active since

2009

Affiliations

Imperial College London(Current)

Hammersmith Hospital

Emory University

Sebastian H. B. Kroll is an author at Imperial College London specializing in cyclin-dependent kinases, cyclin-dependent kinase inhibitors, and pharmacology.

Publications per year

2009–2024

Publications

The Development of a Selective Cyclin-Dependent Kinase Inhibitor That Shows Antitumor Activity

Simak Ali, Dean A. Heathcote, Sebastian H. B. Kroll et al. · Cancer Research · 2009 · 163 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +16

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Hetal Patel, Manikandan Periyasamy, Georgina P. Sava et al. · Molecular Cancer Therapeutics · 2018 · 140 citations · Full text

Medicine, Oncology, Pharmacology +16

A Novel Pyrazolo[1,5-<i>a</i>]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration

Dean A. Heathcote, Hetal Patel, Sebastian H. B. Kroll et al. · Journal of Medicinal Chemistry · 2010 · 103 citations · Full text

Medicine, Oncology, Pharmacology +15

High-resolution cryo-EM of the human CDK-activating kinase for structure-based drug design

Victoria I. Cushing, Fujiet Koh, Junjie Feng et al. · Nature Communications · 2024 · 46 citations · Full text

Life Sciences, Biology, Molecular Biology +15

Inhibitor Selectivity for Cyclin‐Dependent Kinase 7: A Structural, Thermodynamic, and Modelling Study

Pascale Hazel, Sebastian H. B. Kroll, Alexander Bondke et al. · ChemMedChem · 2017 · 40 citations

Life Sciences, Biophysics, Molecular Biology +15

1–5 of 8