Georgina P. Sava

ICEC0942, an Orally Bioavailable Selective Inhibitor of CDK7 for Cancer Treatment

Hetal Patel, Manikandan Periyasamy, Georgina P. Sava et al. · Molecular Cancer Therapeutics · 2018 · 140 citations · Full text

Medicine, Oncology, Pharmacology +16

Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Philip Law, Sonja I. Berndt, Helen E. Speedy et al. · Nature Communications · 2017 · 104 citations · Full text

Life Sciences, Genetics, Molecular Genetics +14

Genetic Predisposition to Chronic Lymphocytic Leukemia Is Mediated by a BMF Super-Enhancer Polymorphism

Radhika Kandaswamy, Georgina P. Sava, Helen E. Speedy et al. · Cell Reports · 2016 · 66 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Active growth signaling promotes senescence and cancer cell sensitivity to CDK7 inhibition

Gemma A. Wilson, Karla Vuina, Georgina P. Sava et al. · Molecular Cell · 2023 · 51 citations · Full text

Medicine, Cancer Biology, Oncology +17

ABC-transporter upregulation mediates resistance to the CDK7 inhibitors THZ1 and ICEC0942

Georgina P. Sava, Hailing Fan, Rosemary A. Fisher et al. · Oncogene · 2019 · 25 citations · Full text

Medicine, Oncology, Pharmacology +15