Pascale Hazel

Loop-Length-Dependent Folding of G-Quadruplexes

Pascale Hazel, J Huppert, Shankar Balasubramanian et al. · Journal of the American Chemical Society · 2004 · 483 citations

Life Sciences, Biochemistry, Biophysics +15

A Novel Pyrazolo[1,5-<i>a</i>]pyrimidine Is a Potent Inhibitor of Cyclin-Dependent Protein Kinases 1, 2, and 9, Which Demonstrates Antitumor Effects in Human Tumor Xenografts Following Oral Administration

Dean A. Heathcote, Hetal Patel, Sebastian H. B. Kroll et al. · Journal of Medicinal Chemistry · 2010 · 103 citations · Full text

Medicine, Oncology, Pharmacology +15

Synthesis and evaluation of analogues of 10H-indolo[3,2-b]quinoline as G-quadruplex stabilising ligands and potential inhibitors of the enzyme telomerase

B�rang�re Guyen, Christoph Schultes, Pascale Hazel et al. · Organic & Biomolecular Chemistry · 2004 · 102 citations

Pharmacy, Chemistry, Medicinal Chemistry +17

Observation of the Coexistence of Sodium and Calcium Ions in a DNA G-Quadruplex Ion Channel

Michael P. H. Lee, Gary N. Parkinson, Pascale Hazel et al. · Journal of the American Chemical Society · 2007 · 74 citations

Life Sciences, Biochemistry, Molecular Biology +13

Topology Variation and Loop Structural Homology in Crystal and Simulated Structures of a Bimolecular DNA Quadruplex

Pascale Hazel, Gary N. Parkinson, Stephen Neidle · Journal of the American Chemical Society · 2006 · 63 citations

Life Sciences, Biochemistry, Molecular Biology +17